Rheumatoid arthritis ⭐
rheumatoid-arthritis · society: ACR · high-yield
Summary
The 2021 ACR guideline updates pharmacologic management of rheumatoid arthritis, covering csDMARDs, bDMARDs, tsDMARDs, glucocorticoids, and DMARD use in high-risk populations (liver disease, heart failure, lymphoproliferative disorder, prior serious infection, NTM lung disease). It includes 44 recommendations (7 strong, 37 conditional). Key changes from 2015 include initial hydroxychloroquine/sulfasalazine for low disease activity, removal of early-vs-established RA subgroups, and a strong push to minimize glucocorticoid exposure.
Current guideline: ACR 2021 RA Treatment Guideline · 
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Versions
- 2021 · ACR — ACR 2021 RA Treatment Guideline