Heparin-induced thrombocytopenia (HIT)
hit · society: ASH
← back to Hematology & Oncology
Summary
ASH 2018 evidence-based guideline on diagnosis and management of heparin-induced thrombocytopenia (HIT), an IgG-mediated prothrombotic reaction to PF4/heparin complexes. The 33 recommendations cover platelet monitoring, use of the 4Ts score with sequential immunoassay/functional assay testing, treatment of acute HIT with non-heparin anticoagulants, and special situations (cardiac surgery, PCI, renal replacement, VTE prophylaxis, history of HIT). Novel features vs prior guidelines: an integrated diagnostic algorithm and explicit inclusion of fondaparinux and DOACs as acceptable options for acute HIT.
Current guideline: ASH 2018 HIT Guideline · 
download Anki sub-deck
Versions
- 2018 · ASH — ASH 2018 HIT Guideline