RBC transfusion thresholds ⭐

rbc-transfusion · society: AABB · high-yield

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Summary

The 2023 AABB international guideline updates RBC transfusion recommendations for hospitalized adults and children based on 45 adult RCTs (n=20,599) and 7 pediatric RCTs (n=2,730). For hemodynamically stable patients, restrictive thresholds (typically Hgb <7 g/dL) are non-inferior to liberal thresholds (9–10 g/dL) for mortality and major morbidity. New since 2016: explicit pediatric recommendations, including separate thresholds by cardiac repair stage in congenital heart disease, and extension of restrictive strategy to hematology/oncology inpatients.

Current guideline: AABB 2023 Red Blood Cell Transfusion Guideline · download Anki sub-deck

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