Hyponatremia

hyponatremia

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Summary

Compilation review comparing the 2013 US expert panel and 2014 European hyponatremia guidelines on diagnosis and treatment of hyponatremia (SNa <136 mmol/L). Both guidelines converge on bolus hypertonic saline for acute/symptomatic hyponatremia and fluid restriction as first-line for chronic hyponatremia, but diverge on diagnostic algorithm (European prioritizes urine osmolality/sodium over volume status), pharmacologic second-line therapy for SIAD, correction-rate limits, and use of vaptans (US permits; European recommends against in profound hyponatremia). Emerging diagnostic markers include fractional uric acid excretion and plasma copeptin.

Current guideline: Hoorn & Zietse 2017 — Diagnosis and Treatment of Hyponatremia (compilation review) · download Anki sub-deck

Versions

• 2017 · JASN — Hoorn & Zietse 2017 — Diagnosis and Treatment of Hyponatremia (compilation review)
  • JASN review compiling the 2014 European (ERBP/ESICM/ESE) and 2013 US expert panel guidelines into a single practical reference. Replaces the inaccessible 2014 European primary guideline as the working source.
  • Read the guideline: html · pmc · Anki deck
• 2013 · US expert panel — 2013 US Expert Panel on Hyponatremia
  • Read the guideline: html

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Table of contents

• 2017 · JASN