Sickle cell disease
sickle-cell
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Summary
ASH 2019 guidelines on cardiopulmonary and kidney disease in sickle cell disease (SCD) address screening and management of pulmonary hypertension, sleep-disordered breathing, abnormal pulmonary function, venous thromboembolism, albuminuria, and chronic kidney disease. The panel generally recommends against routine screening of asymptomatic patients with echocardiography, polysomnography, or pulmonary function testing, favoring targeted evaluation based on signs and symptoms. Recommendations also address anticoagulation duration for VTE, ACEi/ARB use for albuminuria, renal transplant referral, and combined hydroxyurea plus erythropoiesis-stimulating agent therapy for CKD-related anemia.
Current guideline: ASH 2014–2020 Sickle Cell Disease Guideline Series ·
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Versions
- 2020 · ASH — ASH 2014–2020 Sickle Cell Disease Guideline Series
- 2014 · NHLBI — NHLBI 2014 SCD Guideline